Telix Tops ASX Short Sellers List at 16% as Pharma Bets Build

Telix Pharmaceuticals leads the most shorted ASX stocks list at 16.10% short interest as of 28 April 2026, with Generation Development Group and Lotus Resources posting the sharpest weekly buildups while oil, gold, and lithium names saw significant short covering.
By Branka Narancic -
TLX leads ASX most shorted stocks at 16.10%, with DMP at 15.48% and PNV at 14.37% as of 28 April 2026

Key Takeaways

  • Telix Pharmaceuticals (TLX) holds the highest short interest of any ASX-listed stock at 16.10% as of 28 April 2026, up 2.35% over the past month despite strong FY2025 revenue of US$804 million.
  • Generation Development Group (GDG) posted the sharpest weekly move, with short interest surging from approximately 4% to 9.40% in under six weeks following a 22.6% single-session share price drop on 22 April 2026.
  • Lotus Resources (LOT) carries 11.54% short interest and saw shares fall 34% on 30 April 2026 after a fire-related production halt at its Kayelekera uranium mine, an event that occurred after the 28 April measurement date and will not appear until the next data release.
  • Oil, gas, gold, and lithium names including Beach Energy, Genesis Minerals, and Pilbara Minerals saw the most pronounced short covering for the week, reflecting a sector-level divergence from the bearish positioning concentrated in healthcare and consumer names.
  • ASX short data carries a four-business-day lag under ASIC disclosure rules, meaning the 4 May 2026 release reflects positions as of 28 April and any post-date events will only appear in the following week's release.

Three ASX stocks now carry short interest above 14%, with Telix Pharmaceuticals attracting more bearish institutional positioning than any other company on the exchange. Short selling data published by Market Index on 4 May 2026, covering the week to 28 April 2026, reveals a market where pharmaceutical and consumer discretionary names dominate the most shorted list, while oil, gas, and gold miners saw meaningful short covering. The data reflects positions as of 28 April but carries a four-business-day reporting lag under ASIC’s mandatory disclosure rules. What follows is the full top-ten ranking, the week-on-week and month-on-month shifts driving the biggest moves, and what the data signals about institutional sentiment heading into May.

Telix, Domino’s and Polynovo hold the top three positions

Telix Pharmaceuticals (TLX) holds the number-one position with 16.10% short interest, the highest of any ASX-listed stock as of 28 April 2026.

That figure dipped just 0.06% week-on-week but has climbed 2.35% over the past month, up from approximately 11.10% at the start of the calendar year. The trajectory suggests building institutional conviction rather than a one-off spike.

Domino’s Pizza Enterprises (DMP) sits second at 15.48%, slipping 0.07% for the week and 0.54% for the month. Shares remain down roughly 80% from COVID-era peaks and approximately 34% over the past year.

Polynovo (PNV) rounds out the top three at 14.37%, and unlike DMP, the direction is moving against the company. Short interest rose 0.29% week-on-week and 1.59% month-on-month, positioning PNV as the stock where bearish bets are actively expanding.

Top 3 Most Shorted ASX Stocks (As of 28 April 2026)

Stock Short Interest (%) Week-on-Week Change (%) Month-on-Month Change (%)
TLX 16.10 -0.06 +2.35
DMP 15.48 -0.07 -0.54
PNV 14.37 +0.29 +1.59
TWE 13.24 +0.27 -1.41
GYG 12.08 -1.81 -1.41
ZIP 11.76 -0.14 +4.35
FLT 11.68 -0.77 +2.00
LOT 11.54 +0.53 +5.67
CAR 9.89 +0.64 +5.30
GDG 9.40 +1.99 +4.75

What is driving short interest in the top-ranked stocks

The numbers tell part of the story. The thesis behind each position fills in the rest.

TLX‘s short interest has climbed from roughly 11.10% to 16.10% since the start of 2026. The bearish positioning does not appear to be a revenue story; the company reported strong FY2025 figures. Instead, institutional scepticism centres on execution risk in its radiopharmaceutical pipeline and uncertainty around the commercialisation trajectory at scale.

Telix’s FY2025 revenue figures showed US$804 million at the full-year mark, with 46% Q4 growth driven by the Gozellix launch and 19 European marketing authorisations, a commercial track record that makes the bear case almost entirely dependent on whether the therapeutic pipeline delivers.

DMP‘s persistent position near the top of the table reflects concerns about international market execution, a leadership overhaul, and ongoing post-COVID normalisation pressures in discretionary food spending. With shares down approximately 34% over the past year, bears continue to question whether a sustained recovery is achievable.

PNV‘s rising short interest sits in the medical devices and wound care segment. No single confirmed catalyst has publicly emerged to explain the buildup; bears appear to be building positions into the stock’s current valuation without a clear event trigger.

  • TLX: Pipeline execution risk and commercialisation uncertainty despite strong revenue
  • DMP: International market headwinds, leadership changes, and post-COVID normalisation
  • PNV: Rising bearish positioning without a confirmed single catalyst

Treasury Wine Estates (TWE), the next name in the table at 13.24%, reported a $649.4 million net loss for H1 FY2026 and suspended its interim dividend, providing clear fundamental context for sustained bearish conviction.

The biggest weekly movers: where short interest surged and where it covered

Two distinct movements played out in the same week. In one corner, bearish positioning accelerated sharply into several names. In the other, short sellers retreated from commodity-linked stocks.

Where short interest rose most sharply

Generation Development Group (GDG) delivered the most striking move. Short interest climbed from approximately 4% in late March to 9.40% by 28 April 2026, a rise of 1.99% for the week alone and 4.75% for the month. The buildup followed a 22.6% single-session share price drop on 22 April 2026, despite the company reporting funds under management (FUM) of $34.8 billion at end of the March quarter, representing 0.8% quarterly growth.

Lotus Resources (LOT) carries 11.54% short interest, up 0.53% for the week and 5.67% for the month. On 30 April 2026, a fire-related production halt at its Kayelekera uranium mine caused the share price fall. Shares fell 34% on that day.

Zip Co (ZIP) sits at 11.76%, with a monthly increase of 4.35%, and 4DMedical (4DX) rose to 5.31% on a 5.01% monthly climb.

  • GDG: +1.99% weekly, +4.75% monthly; shares fell 22.6% on 22 April
  • LOT: +0.53% weekly, +5.67% monthly; data retraction event on 30 April
  • ZIP: +4.35% monthly
  • 4DX: +5.01% monthly

Where short sellers covered their positions

The resource sector saw the week’s most pronounced covering activity.

The same-week 52-week highs data shows the mirror image of this covering activity: lithium and materials names including Liontown Resources, Pilbara Minerals, and Mineral Resources hit new annual highs, with lithium carbonate averaging $15,000 per tonne in April 2026 providing the fundamental basis for a sector-level divergence from the bearish positioning concentrated in healthcare and consumer names.

Beach Energy (BPT) recorded the largest single-week short cover in the oil and gas segment, falling 3.62% week-on-week to 4.89%. Genesis Minerals (GMD) dropped 2.65% weekly to 2.93%, while PLS Group (PLS) eased 1.31% to 5.49% and Cochlear (COH) fell 1.06% to 4.66%.

Guzman y Gomez (GYG) also saw covering, with short interest declining 1.81% week-on-week to 12.08%. The covering appeared tied to a 36% share price surge between 2 and 10 April 2026, following Q3 Australian comparable sales growth of 6.6% against an estimated 5.1%.

Notable Weekly Short Interest Movers

  • BPT: -3.62% weekly
  • GMD: -2.65% weekly
  • PLS: -1.31% weekly
  • COH: -1.06% weekly
  • GYG: -1.81% weekly

How to read ASX short selling data: what the numbers actually mean

Short interest is expressed as a percentage of a company’s issued shares held in short positions by institutional investors and hedge funds. A figure of 16.10%, as seen with TLX, implies that a meaningful share of the company’s stock is being borrowed and sold by institutions expecting the price to fall.

The data carries a built-in delay. The process works as follows:

  1. A short trade is executed on the ASX.
  2. The trade is reported to ASIC within three business days, as required under mandatory disclosure rules.
  3. ASIC publishes the aggregated data, which reaches platforms like Market Index with a four-business-day lag.

ASIC’s short selling disclosure rules require holders of net short positions above the relevant threshold to report those positions within three business days of the trade, with aggregated data published on a four-business-day lag, which is why the 4 May release captures positions only as of 28 April.

This means data published on 4 May 2026 reflects positions as of 28 April 2026. Any event occurring after that date, such as the LOT data retraction on 30 April, will not appear until the following week’s release.

High short interest reflects institutional bearish conviction. It does not guarantee a price decline. Positions can be held for months, and short sellers can be wrong. Rapidly building short interest, such as GDG‘s doubling in weeks, warrants monitoring rather than immediate action.

Resources for verifying short data include ASIC’s short position reports and ShortMan.com.au, which provides days-to-cover metrics.

The broader market picture: sector patterns in this week’s short data

Stepping back from individual names, the sector-level view reveals where institutional money is expressing the most concentrated scepticism.

The concentration of short interest in healthcare and consumer discretionary names aligns with ASX market breadth data for the same week, where those two sectors produced the most new 52-week lows as consumer confidence posted its steepest monthly decline since the COVID-19 pandemic, reinforcing that institutional short positioning and broader equity weakness are pointing in the same direction.

Healthcare and pharmaceuticals carry the heaviest aggregate short positioning, led by TLX at 16.10% and PNV at 14.29%. Consumer discretionary and food services follow closely, with DMP at 15.48% and GYG at 12.08%.

The retail sector saw building bearish activity across multiple names. Bapcor (BAP) rose to 9.50% (up 1.15% weekly), Myer (MYR) reached 6.59% (up 0.89% weekly), and CAR Group (CAR) climbed to 9.89% (up 0.64% weekly, 5.30% monthly). Zip (ZIP) at 11.76%, with a 4.35% monthly increase, added a buy-now-pay-later name to the list of stocks attracting growing bearish positioning.

On the other side, oil, gas, gold, and lithium names saw the most meaningful short covering. Woodside (WDS) fell to 2.12% (down 0.91% weekly), Evolution Mining (EVN) dropped to 2.53% (down 1.04% weekly), and PLS eased to 5.49% (down 1.31% weekly). Flight Centre (FLT) at 11.68% (down 0.77% weekly but up 2.00% monthly) remains elevated despite the weekly dip.

  • Healthcare/pharma: Heaviest aggregate short interest (TLX, PNV)
  • Consumer discretionary/food: Persistent bearish positioning (DMP, GYG)
  • Retail: Building short interest (BAP, MYR, CAR)
  • Fintech/BNPL: Rising bearish bets (ZIP)
  • Resources (oil, gold, lithium): Most meaningful short covering (WDS, EVN, PLS)

Short sellers are watching the same stocks they watched last month

The top three names, TLX, DMP, and PNV, have held their positions with limited structural change, suggesting institutional conviction in these shorts remains firm rather than being driven by short-term event trading.

The two situations that warrant the closest attention in the coming weeks are Lotus Resources and Generation Development Group. LOT’s data retraction on 30 April 2026, which sent shares down 34%, occurred after the 28 April measurement date. That means the current data does not yet capture any positioning changes prompted by the event. GDG’s short interest has risen from approximately 4% to 9.40% in under six weeks, a pace that stands out against the rest of the table.

Watch list for the next data release: LOT (first data to capture post-retraction positioning) and GDG (monitoring whether the rapid short buildup continues or stabilises).

The next weekly data release will be the first to reflect any market positioning changes from after 28 April 2026. Updated short positions can be accessed via Market Index and ASIC’s published short position reports.

This article is for informational purposes only and should not be considered financial advice. Investors should conduct their own research and consult with financial professionals before making investment decisions.

Frequently Asked Questions

What are the most shorted ASX stocks right now?

As of 28 April 2026, the most shorted ASX stocks are Telix Pharmaceuticals (TLX) at 16.10%, Domino's Pizza Enterprises (DMP) at 15.48%, and Polynovo (PNV) at 14.37%, with Treasury Wine Estates (TWE) and Guzman y Gomez (GYG) also in the top five.

What does high short interest on the ASX mean for investors?

High short interest means a significant percentage of a company's issued shares are being borrowed and sold by institutional investors expecting the price to fall; it reflects bearish conviction but does not guarantee a price decline, as short sellers can hold positions for months and can be wrong.

Why is Telix Pharmaceuticals the most shorted stock on the ASX?

Despite reporting strong FY2025 revenue of US$804 million, Telix Pharmaceuticals carries 16.10% short interest because institutional scepticism centres on execution risk in its radiopharmaceutical pipeline and uncertainty around commercialisation at scale.

How long does it take for ASX short selling data to be published?

ASX short selling data carries a four-business-day reporting lag under ASIC mandatory disclosure rules, which is why the data released on 4 May 2026 only reflects positions as of 28 April 2026 and does not capture events occurring after that date.

Which ASX sectors have the most short selling activity in May 2026?

Healthcare and pharmaceuticals carry the heaviest aggregate short positioning, followed closely by consumer discretionary and food services, while oil, gas, gold, and lithium names experienced the most meaningful short covering during the same period.

Branka Narancic
By Branka Narancic
Partnership Director
Bringing nearly a decade of capital markets communications and business development experience to StockWireX. As a founding contributor to The Market Herald, she's worked closely with ASX-listed companies, combining deep market insight with a commercially focused, relationship-driven approach, helping companies build visibility, credibility, and investor engagement across the Australian market.
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