EBR Systems Presents Five WiSE Sessions at APHRS 2026 Heart Rhythm Meeting

EBR Systems APHRS 2026 presentations put the WiSE wireless pacing system in five scientific sessions in Busan from 21 to 24 October, headlined by real-world data from the first 100 US implants.
By Josua Ferreira -
  • EBR's WiSE System features in five scientific sessions at APHRS 2026 in Busan from 22 to 24 October, spanning three days of the 21 to 24 October event.
  • Dr Niraj Varma will present real-world evidence from the first 100 US commercial implants, showing acute QRS reduction regardless of electrode location.
  • EBR completed 46 commercial implants in Q2 2026, taking the cumulative total to 117 across 30 activated US hospitals.
  • Research on delivering leadless conduction system pacing via WiSE-CRT hints at a potential expansion beyond conventional CRT.
  • The announcement discloses no financial data, and WiSE remains US-only for sale, with a TGA Priority Review Determination cutting Australia's evaluation to roughly 150 working days.
Summarise with AI:

EBR Systems takes WiSE System to APHRS 2026 with five scientific sessions

EBR Systems (ASX: EBR), developer of the world’s only wireless cardiac pacing device for heart failure, announced its participation in the 19th Asia Pacific Heart Rhythm Society Scientific Session (APHRS 2026). The event runs from 21 to 24 October 2026 in Busan, South Korea.

The WiSE System features in five scientific talks, according to the published conference program. Session details are subject to change.

Five WiSE sessions on the program

The schedule below is based on the published conference program, with all times in Korea Standard Time (KST).

Date and time (KST) Presenter Topic
Thursday 22 October, 11:20 AM-11:25 AM Dr Devi Nair Mastering Leadless LV Endocardial Pacing: Expert Strategies for Procedural Success with the WiSE System
Thursday 22 October, 2:00 PM-5:00 PM Dr Simon James Pacing-Induced Severe Functional Mitral Regurgitation After “Ablate & Pace” with a Leadless Pacemaker: Reversal with Endocardial Resynchronisation
Friday 23 October, 9:30 AM-9:40 AM Dr Niraj Varma Leadless LV Endocardial Pacing Delivers Acute QRS Reduction Regardless of Electrode Location: Real-World Evidence from 100 US Implants
Friday 23 October, 2:00 PM-5:00 PM Alphonsus Liew, MBBS, MRCP, PhD A Mechanistic Haemodynamic and Electrical Study to Support the use of Leadless Left-sided Conduction System Pacing Delivered via the WISE-CRT System
Saturday 24 October, 8:30 AM-8:45 AM Dr Nestor Lopez-Cabanillas Is LV Endocardial Pacing an Alternative for CRT?

Management commentary

John McCutcheon, President & Chief Executive Officer of EBR Systems, said the presentations reflect the company’s focus on clinical evidence and physician support.

John McCutcheon, President & Chief Executive Officer

“APHRS 2026 provides an important opportunity to share our growing commercial experience with the WiSE® System and explore its potential to expand pacing options for patients… These presentations reflect our focus on building clinical evidence and supporting physicians as they adopt WiSE.”

McCutcheon said the presentations will include:

  • Data from the first 100 U.S. commercial patients
  • Research exploring the use of WiSE to deliver leadless conduction system pacing
  • Consensus strategies from six experienced implanters to optimise procedural success

The commercial experience feeding these presentations continues to build, with EBR completing 46 commercial implants in the second quarter of 2026 and lifting its cumulative total to 117 across 30 activated US hospitals.

What is leadless left ventricular endocardial pacing?

Cardiac Resynchronisation Therapy (CRT) treats heart failure patients who need coordinated pacing of the heart. Conventional approaches use a pacing wire on the outside of the heart’s left ventricle, and leads have historically been the major source of complications, effectiveness and reliability issues in cardiac rhythm disease management.

Conventional vs. WiSE Endocardial Pacing

WiSE stimulates the left ventricle from inside the heart (endocardial) using a novel cardiac implant roughly the size of a large grain of rice. According to the company, WiSE is the world’s only wireless, endocardial pacing system in clinical use for stimulating the heart’s left ventricle, and internal stimulation is thought to be a potentially superior, more anatomically correct pacing location.

Why it matters for investors

The APHRS 2026 sessions align with the company’s stated focus on building clinical evidence and supporting physicians as they adopt WiSE. The announcement does not disclose financial data or address revenue or regulatory implications.

WiSE is an investigational device in most markets and is currently only available for sale in the US. More information is available on the EBR Systems website.

Outside the US, EBR has secured a TGA Priority Review Determination, cutting the Australian evaluation period from 225 to roughly 150 working days and positioning Australia as its second major market target.

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Frequently Asked Questions

What is leadless left ventricular endocardial pacing?

It is a way to pace the heart's left ventricle from the inside using a wireless implant roughly the size of a large grain of rice, rather than a lead on the outside of the heart. EBR's WiSE System is described by the company as the world's only wireless endocardial pacing system in clinical use.

When and where is APHRS 2026 being held?

The 19th Asia Pacific Heart Rhythm Society Scientific Session runs from 21 to 24 October 2026 in Busan, South Korea. EBR's WiSE System features in five sessions between 22 and 24 October.

What will EBR Systems present at APHRS 2026?

Presentations include data from the first 100 US commercial patients, research on using WiSE for leadless conduction system pacing, and consensus strategies from six experienced implanters. Session details are subject to change.

Where can the WiSE System currently be bought?

WiSE is investigational in most markets and is currently only available for sale in the US. EBR has also secured a TGA Priority Review Determination in Australia, cutting the evaluation period from 225 to roughly 150 working days.

How many WiSE implants has EBR Systems completed?

EBR completed 46 commercial implants in the second quarter of 2026, lifting its cumulative total to 117 across 30 activated US hospitals.

Josua Ferreira
By Josua Ferreira
Partnership Director
Josua Ferreira holds a Bachelor of Commerce in Marketing and Advertising and brings a background in publication, business development, and ASX market storytelling. He has worked with listed companies across the resource sector and broader market, combining sharp commercial instincts with a genuine commitment to keeping investors informed.
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