4DMedical Eyes $2.5B PE Market as CLEAR Program Targets 5M Annual US Scans
4DMedical has launched the CLEAR program targeting the US$2.5 billion acute pulmonary embolism imaging market, partnering with Massachusetts General Hospital to build clinical evidence for its contrast-free CT:VQ™ technology and potentially expand its U.S. addressable market sixfold to US$3 billion.
Key Takeaways
- 4DMedical has launched the CLEAR clinical evidence program to target the approximately 5 million annual U.S. CTPA scans performed for suspected acute pulmonary embolism, a market valued at approximately US$2.5 billion
- Massachusetts General Hospital, the largest Harvard Medical School teaching hospital, will serve as the principal enrolling site under a clinical research agreement funded by approximately US$2 million committed by 4DMedical
- Successful execution of CLEAR would expand 4DMedical's combined U.S. obtainable market sixfold to US$3 billion by adding the CTPA-dominated PE segment to its existing nuclear VQ replacement opportunity
- CT:VQ™ is already FDA-cleared for the underlying VQ indication, meaning CLEAR is designed to build adoption evidence rather than seek new regulatory approval, reducing execution risk for the program
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