Cambium Bio Targets $10.85M Funding Package for Phase 3 Eye Drug Trial

Cambium Bio Elate Ocular funding reaches A$10.85 million through a premium-priced placement and non-dilutive RDTI pre-financing, giving the company the capital to run its pivotal Phase 3 CAMOMILE-3 dry eye trial after the FDA cleared a single-study pathway to a Biologics License Application.
By Josua Ferreira -
  • Cambium Bio has secured a total A$10.85 million funding package comprising a A$7.1 million conditional placement at A$0.48 per share — a 4.3% premium to the prior close — and a A$3.75 million RDTI pre-financing facility.
  • The FDA's April 2026 confirmation of a single pivotal trial pathway to a Biologics License Application replaced the historical dual-study requirement, materially reducing the total capital needed to reach potential market authorisation for Elate Ocular®.
  • The placement is conditional on shareholder approval at the November 2026 AGM, with all three resolutions inter-conditional — if any one fails by 30 November 2026, the entire placement lapses.
  • ZYBT, Cambium Bio's largest shareholder and strategic partner, is participating to maintain approximately its existing position, continuing a pattern of premium-priced support that began with its January 2026 investment at a 20% premium.
  • The A$3.75 million RDTI facility, executed with Rockford RDF Pty Ltd on 5 August 2026 and secured solely over the FY2027 RDTI refund receivable, is non-dilutive — no additional shares are issued for this tranche.
Summarise with AI:

A$10.85 million funding package advances Elate Ocular® Phase 3 program

Cambium Bio Limited (ASX: CMB) has received firm commitments to raise A$7.1 million through a conditional placement, which, combined with an A$3.75 million Research and Development Tax Incentive (RDTI) pre-financing facility, delivers a total funding package of A$10.85 million to advance its pivotal Phase 3 program for Elate Ocular® in moderate to severe dry eye disease.

The placement involves the issue of 14,791,667 new fully paid ordinary shares at A$0.48 per share, a price representing a 4.3% premium to the company’s closing share price of A$0.46 on 15 September 2026. The premium pricing signals investor confidence rather than a discounted raise. The placement is conditional on shareholder approval at the 2026 Annual General Meeting (AGM), expected to be held in mid to late November 2026.

Proceeds from the combined funding package are intended for the pivotal Phase 3 trial of Elate Ocular®, Phase 3 manufacturing, regulatory activities, and general working capital.

Cambium Bio A$10.85M Funding Package Breakdown

The capital raised will fund the CAMOMILE-3 study, a programme whose design was shaped by the FDA’s April 2026 confirmation of a single pivotal trial pathway to a Biologics License Application, replacing the historical dual-study requirement and materially reducing the total capital needed to reach potential market authorisation.

Strategic shareholder backing anchors the placement

The placement draws capital from four participants, combining continued support from existing shareholders with new strategic investment:

  • ZYBT (Zheng Yang Biomedical Technology Co., Ltd.) — Cambium Bio’s largest shareholder and long-standing strategic partner, participating to maintain approximately its existing shareholding (voting power expected to decrease slightly from approximately 36.78% to approximately 35.06% post-placement).
  • Mr Chun Yi (Brandon) Wu — an existing shareholder increasing his position.
  • Ms Yi Chi Wu — a new investor and associate of Mr Wu.
  • Ms Shu-Chin (Tiffany) Hsu — a new investor.

Mr Wu and Ms Yi Chi Wu are associates. Their combined voting power is expected to increase from approximately 18.51% to approximately 31.85%, requiring shareholder approval under item 7 of section 611 of the Corporations Act, supported by an independent expert’s report.

ZYBT is a related party of the company, given that Non-Executive Director Dr Sebastian Tseng is Executive Chairman of ZYBT. The issue of placement shares to ZYBT therefore requires shareholder approval under ASX Listing Rule 10.11. The Board, with Dr Tseng abstaining, has determined that the terms of the placement are on arm’s length terms. No placement capacity under ASX Listing Rules 7.1 or 7.1A is used. No lead manager, broker, or external adviser was engaged, and transaction costs are nominal.

ZYBT’s prior strategic investment in January 2026, made at a 20% premium and directed toward initiating Phase 3 patient dosing, established the pattern of premium-priced participation that the current placement continues, reinforcing the strategic partner’s long-term alignment with Elate Ocular’s development.

Participant Shares held before Voting power before Placement shares Shares held after Voting power after
ZYBT 10,826,136 36.78% 4,677,444 15,503,580 35.06%
Chun Yi (Brandon) Wu 5,448,000 18.51% 2,733,363 8,181,363 18.50%
Yi Chi Wu nil 5,901,693 5,901,693 13.35%
Shu-Chin (Tiffany) Hsu nil 1,479,167 1,479,167 3.34%
Total 14,791,667

Voting power figures are approximate, calculated on 29,431,918 shares on issue before the placement and 44,223,585 shares after, assuming all four tranches are issued.

Understanding RDTI pre-financing — what it means for investors

The RDTI is a federal government programme that refunds a percentage of eligible research and development expenditure to qualifying companies. Rather than waiting for the Australian Taxation Office (ATO) to process that refund at the end of the financial year, pre-financing allows a company to borrow against the expected refund now, accessing capital sooner.

Cambium Bio executed the A$3.75 million secured facility with Rockford RDF Pty Ltd on 5 August 2026, secured over the FY2027 RDTI refund receivable and its proceeds only. The facility was undrawn as at the date of the announcement.

From an investor perspective, pre-financing the RDTI refund means Cambium Bio accesses non-dilutive capital without issuing additional shares for this tranche. It preserves equity while accelerating the funds available to support the Phase 3 programme.

Timetable, next steps, and what investors should watch

The key milestones for the placement are as follows:

  1. Announcement of the placement and Appendix 3B — 15 September 2026
  2. Notice of AGM, including the independent expert’s report, dispatched to shareholders — mid/late October 2026
  3. 2026 Annual General Meetingmid/late November 2026
  4. Subscription monies due — within three business days after the AGM
  5. Placement shares issued and quoted on ASX — within five business days after the AGM
  6. Lapse date if approvals not obtained — 30 November 2026

The three shareholder resolutions (covering the issues to ZYBT, Mr Wu and Ms Yi Chi Wu, and Ms Hsu) are inter-conditional. If any one resolution is not passed by 30 November 2026, the placement will not proceed for any participant. For investors, the November AGM represents the key near-term catalyst to watch.

CEO Karolis Rosickas

“This placement brings together continued support from our largest shareholder, ZYBT, and from Mr Wu, alongside new investment from Ms Wu and Ms Hsu, and reflects sustained confidence in Elate Ocular® and our pivotal Phase 3 program. Together with the RDTI pre-financing facility, it gives Cambium Bio an A$10.85 million funding package to initiate and run the pivotal trial. We look forward to putting the placement resolutions to shareholders at our Annual General Meeting.”

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Frequently Asked Questions

What is the Cambium Bio Elate Ocular funding package announced in September 2026?

Cambium Bio announced a total A$10.85 million funding package comprising a A$7.1 million conditional placement at A$0.48 per share and a A$3.75 million RDTI pre-financing facility, both intended to fund the pivotal Phase 3 CAMOMILE-3 trial for Elate Ocular® in moderate to severe dry eye disease.

What is RDTI pre-financing and why does it matter for Cambium Bio investors?

RDTI pre-financing allows a company to borrow against its expected federal R&D tax refund before the ATO processes it at year-end, giving Cambium Bio access to A$3.75 million in non-dilutive capital — meaning no additional shares are issued for this portion of the funding package.

When will Cambium Bio shareholders vote on the placement?

The shareholder vote is expected at the 2026 Annual General Meeting in mid to late November 2026, with all three placement resolutions inter-conditional — if any one fails by 30 November 2026, the entire A$7.1 million placement lapses.

Why did the FDA's single pivotal trial decision matter for the Elate Ocular Phase 3 program?

The FDA's April 2026 confirmation of a single pivotal trial pathway to a Biologics License Application replaced the previous dual-study requirement, materially reducing the total capital Cambium Bio needs to reach potential market authorisation for Elate Ocular®.

Who are the investors participating in the Cambium Bio placement?

The four participants are ZYBT (Cambium Bio's largest shareholder, maintaining approximately its existing 35% position), existing shareholder Mr Chun Yi Wu (increasing his stake), and two new investors — Ms Yi Chi Wu (an associate of Mr Wu) and Ms Shu-Chin Hsu — all subscribing at A$0.48 per share.

Josua Ferreira
By Josua Ferreira
Partnership Director
Josua Ferreira holds a Bachelor of Commerce in Marketing and Advertising and brings a background in publication, business development, and ASX market storytelling. He has worked with listed companies across the resource sector and broader market, combining sharp commercial instincts with a genuine commitment to keeping investors informed.
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