Imugene Azer-cel Posts 77% Response in 56 Phase 1b Patients [VIDEO]

Imugene azer-cel clinical progress now spans 140 treated patients, a 77% response rate in the later trial and a cost base cut by about 40%.

By Josua Ferreira -

Key Takeaways

  • Imugene has treated 140 patients with azer-cel, with a 77% response rate in 56 patients with B-cell cancers in the later trial.
  • The later trial reported no graft-versus-host disease and no severe immune reactions at the higher grades.
  • Early combination data for patients who stopped responding to older drugs shows 6 of 7 responding, a very small group the company calls early.
  • Key dates are December 2026 for new data, mid 2027 for a US regulator meeting and a final-stage study starting in the second half of 2027 or 2028.
  • The company has cut its cost base by about 40%, saved $4.2 million in pay costs and says licensing talks are underway.
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