Syntara Pauses Scar Trial Recruitment After Skin Irritation Reports [VIDEO]

Syntara has paused recruitment in its SNT-9465 Phase 1b scar study after reports of mild to moderate skin irritation, and will decide this quarter whether the study restarts or ends.

By Josua Ferreira -

Key Takeaways

  • Syntara has paused recruitment in its SNT-9465 Phase 1b scar study after reports of mild to moderate skin irritation in some patients.
  • The company will review unblinded data from completed and ongoing patients, and expects to finish that review this quarter.
  • After the review, Syntara will either restart recruitment or end the study.
  • The study had recently grown from 20 to 30 participants, with first results expected in the first three months of 2027.
  • Amsulostat, the lead drug, is still moving ahead in myelofibrosis, with a Phase 2b trial of roughly 100 patients supported by FDA feedback.
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