Imugene Doses First Patient in BTKi Combo Cohort of Azer-Cel Cancer Trial
Imugene has dosed the first patient in its azer-cel BTKi combination trial cohort, targeting a US$12 billion market of BTKi-relapsed B-cell malignancy patients with limited treatment options.
Key Takeaways
- Imugene has dosed the first patient in the BTKi combination cohort of its azer-cel Phase 1b study at Baylor University, expanding the trial into a third treatment arm.
- The new cohort targets BTKi-relapsed patients across B-cell malignancies including mantle cell lymphoma, follicular lymphoma, and chronic lymphocytic leukemia — a combined global market of approximately US$12.0 billion in 2025.
- Enrolment is active across 15 sites in the US and Australia, with safety and preliminary efficacy data to be reported as patients become evaluable.
- The basket trial design across CAR T relapsed, CAR T naïve, and now BTKi-relapsed cohorts creates multiple development pathways and may strengthen future partnering discussions.
This is a special feature video produced for our partner.
Topic Hubs